Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724859 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1ALOX15SMN1; SMN2 | |
| SCHEMBL9724808 | 0.85 | MEN1 (0.53) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL5037571 | 0.84 | MAPK1 (0.63) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL5162575 | 0.83 | BACE1 (0.56) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL5162582 | 0.83 | BACE1 (0.56) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9724829 | 0.82 | BACE1 (0.54) | NPC1RAB9AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9724978 | 0.81 | KMT2A (0.52) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9724923 | 0.81 | RAB9A (0.50) | NPC1RAB9AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6410493 | 0.81 | MMP1 (0.57) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9724810 | 0.81 | MME (0.54) | ALDH1A1NPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |