Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | FPR2 | P25090 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KLK7 | P49862 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724920 | 0.85 | RAB9A (0.67) | KMT2ARAB9AALDH1A1MAPTPOLB | |
| SCHEMBL9724808 | 0.85 | MEN1 (0.53) | KMT2ARAB9AALDH1A1MAPTPOLB | |
| SCHEMBL5037571 | 0.84 | MAPK1 (0.63) | KMT2ARAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9724801 | 0.84 | HPGD (0.56) | KMT2ARAB9AALDH1A1SMN1; SMN2KLK7 | |
| SCHEMBL6665555 | 0.83 | KMT2A (0.65) | KMT2AL3MBTL1FPR2RAB9AALDH1A1 | |
| SCHEMBL30452307 | 0.83 | KMT2A (0.65) | KMT2AL3MBTL1FPR2RAB9AALDH1A1 | |
| SCHEMBL28917901 | 0.83 | KMT2A (0.68) | KMT2AL3MBTL1FPR2RAB9AALDH1A1 | |
| SCHEMBL28119598 | 0.83 | KMT2A (0.65) | KMT2AL3MBTL1FPR2RAB9AALDH1A1 | |
| SCHEMBL9724829 | 0.82 | BACE1 (0.54) | KMT2ARAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9724923 | 0.81 | RAB9A (0.50) | KMT2ARAB9AMAPTSMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |