Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 6/20 | 0.54 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727135 | 0.82 | DRD4 (0.67) | CYP3A4DRD4MAOB | |
| SCHEMBL9727202 | 0.80 | KCNH2 (0.47) | DRD4NPC1RAB9A | |
| Dimethylamine SCHEMBL9852061 | 0.80 | DRD4 (0.63) | DRD4MAOB | |
| SCHEMBL9727123 | 0.80 | DRD4 (0.69) | DRD4MAOB | |
| SCHEMBL9727173 | 0.80 | SIGMAR1 (0.57) | DRD4MAOB | |
| SCHEMBL9343970 | 0.79 | CCR1 (0.41) | CCR1HTR4DRD4MAOB | |
| SCHEMBL9727255 | 0.78 | DRD4 (0.66) | DRD4MAOB | |
| SCHEMBL9727095 | 0.77 | DRD4 (0.72) | DRD4MAOB | |
| SCHEMBL9727126 | 0.76 | RAB9A (0.70) | CCR1CHRM2CHRM1CHRM3NPC1 | |
| SCHEMBL9852073 | 0.76 | DRD4 (0.54) | DRD4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |