Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727442 | 0.81 | LMNA (0.61) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9727392 | 0.80 | LMNA (0.59) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9727309 | 0.75 | HTR6 (0.49) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9727328 | 0.74 | KMT2A (0.47) | LMNAHTTSMN1; SMN2MEN1CYP2D6 | |
| SCHEMBL16400474 | 0.72 | CA2 (0.45) | SMN1; SMN2MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL16401187 | 0.72 | KMT2A (0.45) | SMN1; SMN2MEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL10702282 | 0.70 | MMP2 (0.64) | KMT2APOLBAKR1C3TP53GAA | |
| SCHEMBL7379601 | 0.70 | MMP2 (0.64) | LMNASMN1; SMN2MEN1KMT2AAKR1C3 | |
| SCHEMBL7383735 | 0.70 | MMP2 (0.64) | LMNAHTTSMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL7380549 | 0.70 | PKM (0.62) | LMNAMEN1CYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |