Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727516 | 0.85 | NR1I2 (0.33) | NR1I2MAOAPTGS2OPRK1SLC6A3 | |
| SCHEMBL9727743 | 0.80 | HTR6 (0.40) | — | |
| SCHEMBL9727764 | 0.80 | IGF1R (0.35) | TBXA2RHRH4HRH3 | |
| SCHEMBL14435033 | 0.73 | HTR6 (0.43) | — | |
| SCHEMBL14446494 | 0.73 | HTR6 (0.38) | — | |
| SCHEMBL9727620 | 0.73 | CCR5 (0.38) | — | |
| SCHEMBL14435032 | 0.71 | MTNR1A (0.38) | — | |
| SCHEMBL14435039 | 0.69 | AKR1B1 (0.40) | — | |
| SCHEMBL9727677 | 0.69 | PTGDR2 (0.38) | MAOA | |
| SCHEMBL9727775 | 0.68 | TBXA2R (0.45) | SLC6A3TBXA2RHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |