Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435039 | 0.88 | AKR1B1 (0.40) | — | |
| SCHEMBL9727677 | 0.84 | PTGDR2 (0.38) | — | |
| SCHEMBL9727669 | 0.81 | MTNR1A (0.43) | — | |
| SCHEMBL9727743 | 0.81 | HTR6 (0.40) | — | |
| SCHEMBL9727728 | 0.80 | NR1I2 (0.32) | TBXA2RHRH4HRH3 | |
| SCHEMBL9727775 | 0.78 | TBXA2R (0.45) | TBXA2RHRH4HRH3 | |
| SCHEMBL5506271 | 0.76 | MAOA (0.41) | — | |
| SCHEMBL14435033 | 0.73 | HTR6 (0.43) | — | |
| SCHEMBL14435032 | 0.72 | MTNR1A (0.38) | — | |
| SCHEMBL5505040 | 0.71 | AKR1B1 (0.37) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |