Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506271 | 0.93 | MAOA (0.41) | FFAR1MAOAMAOB | |
| SCHEMBL9727764 | 0.84 | IGF1R (0.35) | — | |
| SCHEMBL27739159 | 0.83 | MAOB (0.41) | MAOAMAOB | |
| SCHEMBL9727650 | 0.82 | KDM1A (0.41) | — | |
| SCHEMBL9727669 | 0.82 | MTNR1A (0.43) | — | |
| SCHEMBL9727674 | 0.81 | LTB4R (0.38) | FFAR1PPARGMAOAMAOB | |
| SCHEMBL14435039 | 0.80 | AKR1B1 (0.40) | — | |
| SCHEMBL5518490 | 0.80 | F2 (0.41) | FFAR1PPARGPPARDMAOAMAOB | |
| SCHEMBL9727749 | 0.79 | MAOA (0.34) | MAOAMAOB | |
| SCHEMBL9727668 | 0.77 | TDP1 (0.36) | PTGDR2TDP1L3MBTL1FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |