Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728470 | 0.91 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL9728142 | 0.86 | MEN1 (0.56) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL9729063 | 0.86 | MAPK1 (0.57) | RAB9ANPC1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9728332 | 0.82 | MAPT (0.52) | RAB9ANPC1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL9728645 | 0.81 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL16201551 | 0.74 | PDE11A (0.84) | RAB9ANPC1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL7224007 | 0.74 | EGFR (0.50) | RAB9ANPC1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL17383210 | 0.73 | ALDH1A1 (0.56) | RAB9ANPC1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL14773948 | 0.72 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL29510945 | 0.72 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |