Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728470 | 0.87 | RAB9A (0.68) | MAPK1TP53NPC1RAB9AKMT2A | |
| SCHEMBL9728272 | 0.86 | RAB9A (0.56) | MAPK1TP53NPC1RAB9AKMT2A | |
| SCHEMBL9728142 | 0.78 | MEN1 (0.56) | NPC1RAB9AKMT2AMAPTADORA3 | |
| SCHEMBL9728332 | 0.76 | MAPT (0.52) | MAPK1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL16201550 | 0.76 | PDE11A (0.79) | MAPK1TP53IRAK4NPC1RAB9A | |
| SCHEMBL20942205 | 0.73 | NPC1 (0.60) | MAPK1TP53NPC1RAB9AKMT2A | |
| SCHEMBL9728959 | 0.73 | RAB9A (0.72) | TP53NPC1RAB9AKMT2AMAPT | |
| SCHEMBL3604861 | 0.72 | IRAK4 (0.80) | TP53IRAK4NPC1RAB9AKMT2A | |
| SCHEMBL21105717 | 0.71 | IRAK4 (1.00) | TP53IRAK4NPC1RAB9AKMT2A | |
| SCHEMBL7224007 | 0.71 | EGFR (0.50) | TP53NPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |