Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728470 | 0.87 | RAB9A (0.68) | MEN1KMT2APOLBMAPTNPC1 | |
| SCHEMBL9728272 | 0.86 | RAB9A (0.56) | MEN1KMT2APOLBMAPTNPC1 | |
| SCHEMBL19662758 | 0.84 | RAB9A (0.75) | MEN1KMT2APOLBMAPTNPC1 | |
| SCHEMBL9728332 | 0.79 | MAPT (0.52) | KMT2AMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL9729063 | 0.78 | MAPK1 (0.57) | KMT2AMAPTNPC1RAB9AADORA3 | |
| SCHEMBL11702983 | 0.78 | NPC1 (0.52) | MEN1KMT2APOLBMAPTNPC1 | |
| SCHEMBL7217219 | 0.73 | L3MBTL1 (0.54) | MEN1KMT2AL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL9728665 | 0.73 | NPC1 (0.57) | MEN1KMT2ANPC1RAB9AGRM5 | |
| SCHEMBL4285475 | 0.71 | KMT2A (0.67) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL19662755 | 0.71 | RPS6KA2 (0.52) | MEN1KMT2APOLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |