Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728348 | 0.70 | SMN1; SMN2 (0.37) | CFTR | |
| SCHEMBL3192879 | 0.68 | CFTR (0.39) | CFTR | |
| SCHEMBL9728417 | 0.68 | L3MBTL1 (0.43) | MEN1KMT2A | |
| SCHEMBL10961509 | 0.66 | LMNA (0.44) | CFTRMEN1KMT2A | |
| Levodropropizine SCHEMBL29043 | 0.63 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| Dropropizine SCHEMBL93975 | 0.63 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| Dropropizine SCHEMBL8379428 | 0.63 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| Dropropizine SCHEMBL27495915 | 0.62 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CMEN1KMT2A | |
| SCHEMBL1230085 | 0.61 | CFTR (0.59) | CFTRMEN1KMT2A | |
| SCHEMBL16361382 | 0.61 | SIGMAR1 (0.40) | CFTRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098926-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-4888341-A | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-12-19 | — | — | US | disclosed |