Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.70 |
| ▸ | RAB9A | P51151 | 13/20 | 0.70 |
| ▸ | PKM | P14618 | 5/20 | 0.70 |
| ▸ | KLF5 | Q13887 | 3/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728941 | 0.89 | NPC1 (0.67) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL30387611 | 0.87 | NPC1 (0.70) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9728591 | 0.87 | NPC1 (0.59) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9729182 | 0.87 | NPC1 (0.70) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9728665 | 0.86 | NPC1 (0.57) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9728959 | 0.86 | RAB9A (0.72) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9728432 | 0.85 | NPC1 (0.56) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL11706816 | 0.82 | NPC1 (1.00) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL9729002 | 0.82 | ALPL (0.51) | NPC1RAB9APKMKLF5OPRK1 | |
| SCHEMBL7456210 | 0.80 | LMNA (0.65) | NPC1RAB9APKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201206-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | THE PENN STATE RESEARCH FOUNDATION | 2023-06-29 | — | — | US | disclosed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201206-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | CLPP, SPOUT1, CASP3 | NPC1 1243/4885RAB9A 2358/4885PKM 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.