Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368477 | 0.75 | SIGMAR1 (0.42) | SIGMAR1MTNR1AMTNR1BTP53FFAR4 | |
| SCHEMBL9722865 | 0.74 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL30779196 | 0.71 | CA2 (0.40) | SIGMAR1CA2CA1 | |
| SCHEMBL9730098 | 0.69 | ALOX5 (0.40) | SIGMAR1ALDH1A1 | |
| Formamide SCHEMBL9731301 | 0.69 | CA2 (0.61) | CA2 | |
| SCHEMBL11668662 | 0.68 | MTNR1A (0.36) | SIGMAR1MTNR1ACA2MTNR1BALDH1A1 | |
| SCHEMBL11129686 | 0.67 | SIGMAR1 (0.44) | SIGMAR1MAOAMAOB | |
| Formamide SCHEMBL9729914 | 0.67 | KDM4C (0.49) | — | |
| SCHEMBL6721448 | 0.66 | SIGMAR1 (0.43) | SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL8818299 | 0.65 | ALDH1A1 (0.43) | SIGMAR1MTNR1AMTNR1BALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |