Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689917 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KMT2AHPGDHSD17B10TSHR | |
| SCHEMBL9690103 | 0.77 | ALDH1A1 (0.43) | TRPV1KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL5966689 | 0.76 | TRPV1 (0.59) | TRPV1KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL8947317 | 0.74 | ALDH1A1 (0.57) | TRPV1KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL8947250 | 0.74 | TRPV1 (0.48) | TRPV1KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL8947310 | 0.74 | TRPV1 (0.63) | TRPV1KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL8947336 | 0.73 | TRPV1 (0.56) | TRPV1KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL8947264 | 0.72 | P2RX7 (0.49) | TRPV1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8947228 | 0.72 | MAPK1 (0.40) | TRPV1ALDH1A1HPGDMAPK1CYP1A2 | |
| SCHEMBL9688895 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1KMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4297474-A | — | — | None | — | — | JP | disclosed |
| JP-H04297474-A | TETRAZOLEACETIC ACID DERIVATIVE | WAKAMOTO PHARMACEUT CO LTD | 1992-10-21 | — | — | JP | disclosed |