Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734017 | 0.87 | ALDH1A1 (0.48) | HIF1AIDO1TDO2IDO2CA2 | |
| SCHEMBL9734163 | 0.86 | HIF1A (0.48) | HIF1AIDO1TDO2IDO2CA2 | |
| SCHEMBL9733469 | 0.83 | MAPT (0.44) | HIF1AIDO1TDO2IDO2MAPT | |
| SCHEMBL9733292 | 0.79 | MEN1 (0.45) | HIF1AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9733574 | 0.77 | KMT2A (0.45) | HIF1AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9733634 | 0.77 | ALDH1A1 (0.54) | HIF1AADORA2AADORA1CA2MEN1 | |
| SCHEMBL9733389 | 0.73 | ALDH1A1 (0.42) | HIF1AIDO1TDO2IDO2MAPT | |
| SCHEMBL9733681 | 0.71 | ALDH1A1 (0.45) | IDO1TDO2IDO2HPGDALDH1A1 | |
| SCHEMBL9737918 | 0.71 | ALDH1A1 (0.62) | HIF1AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9733850 | 0.70 | ALDH1A1 (0.41) | CA2MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |