Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC10A2 | Q12908 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | FSHR | P23945 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735080 | 0.86 | TSHR (0.42) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL9733666 | 0.85 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL9733350 | 0.82 | HIF1A (0.41) | ALDH1A1MAPTMAPK1DRD2HTR2A | |
| SCHEMBL9734096 | 0.82 | ABCC9 (0.41) | DRD2 | |
| SCHEMBL10512304 | 0.81 | SLC10A2 (0.33) | DRD1SLC10A2TMEM97SIGMAR1FSHR | |
| SCHEMBL10512313 | 0.81 | SLC10A2 (0.33) | DRD1SLC10A2TMEM97SIGMAR1FSHR | |
| SCHEMBL10512306 | 0.81 | SLC10A2 (0.33) | DRD1SLC10A2TMEM97SIGMAR1FSHR | |
| SCHEMBL9732909 | 0.81 | OPRD1 (0.35) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL9737119 | 0.81 | MAOA (0.40) | KDM4EALDH1A1MAPTSIGMAR1HTR2A | |
| SCHEMBL9735412 | 0.74 | ABCC9 (0.32) | SLC10A2DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132307-A | TETRALIN COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-21 | — | — | US | disclosed |
| EP-0368160-A1 | Tetralin derivatives | MERCK PATENT GmbH (DE) | 1990-05-16 | — | — | EP | disclosed |