Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792255 | 0.84 | — | — | |
| SCHEMBL9689195 | 0.81 | CASP3 (0.36) | CASP3SENP8SENP7SENP6CXCR1 | |
| SCHEMBL9689827 | 0.80 | CASP3 (0.35) | CASP3SENP8SENP7SENP6CXCR1 | |
| SCHEMBL9687956 | 0.80 | CASP3 (0.35) | CASP3SENP8SENP7SENP6CXCR1 | |
| SCHEMBL9689783 | 0.79 | TSHR (0.36) | — | |
| SCHEMBL9689213 | 0.77 | KMT2A (0.39) | — | |
| SCHEMBL8812100 | 0.76 | RECQL (0.50) | — | |
| SCHEMBL9688728 | 0.74 | MAPK1 (0.38) | CASP3SENP8SENP7SENP6CXCR1 | |
| SCHEMBL9689312 | 0.74 | CASP3 (0.34) | CASP3SENP8SENP7SENP6CXCR1 | |
| SCHEMBL9689958 | 0.74 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082951-A | Process for preparing 5-aroyl-2,3-dihydro-1H-pyrrolizine-1,1-dicarboxylates (I) and intermediates therefor | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |