Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ICMT | O60725 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732159 | 0.81 | KDM4E (0.48) | PLA2G2AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9733084 | 0.80 | P2RX7 (0.52) | PLA2G2AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9733077 | 0.79 | ICMT (0.48) | PLA2G2AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9732157 | 0.78 | PLA2G2A (0.49) | PLA2G2AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9731975 | 0.73 | P2RX7 (0.54) | PLA2G2AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9733238 | 0.71 | ALDH1A1 (0.52) | KDM4EALDH1A1KMT2AMAPTNTSR1 | |
| SCHEMBL9731969 | 0.71 | ICMT (0.50) | PLA2G2AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9733384 | 0.71 | PLA2G2A (0.55) | PLA2G2AALDH1A1LMNAICMTHTR6 | |
| SCHEMBL9733317 | 0.71 | P2RX7 (0.52) | PLA2G2AKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL9732883 | 0.70 | PLA2G2A (0.62) | PLA2G2AALDH1A1LMNAHTR6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | claimed |