SCHEMBL9735290

SCHEMBL9735290

CCC(=O)/C=C/c1ccc(O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 3/20 0.74
AKR1B10 O60218 2/20 0.74
MAOB P27338 2/20 0.74
PTGS2 P35354 1/20 0.74
GLO1 Q04760 1/20 0.74
CAMK2A Q9UQM7 1/20 0.74
IAPP P10997 1/20 0.66
TYR P14679 3/20 0.61
F3 P13726 2/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
HSD11B1 P28845 1/20 0.61
CA12 O43570 3/20 0.61
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA7 P43166 3/20 0.61
CA9 Q16790 3/20 0.61
CA14 Q9ULX7 3/20 0.61
ESR1 P03372 1/20 0.59
CA3 P07451 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9735291 1.00 AKR1B1 (0.74) AKR1B1AKR1B10MAOBPTGS2GLO1
Bisdemethoxycurcumin SCHEMBL428638 0.85 AKR1B1 (1.00) AKR1B1AKR1B10MAOBPTGS2GLO1
Bisdemethoxycurcumin SCHEMBL2574140 0.85 AKR1B1 (1.00) AKR1B1AKR1B10MAOBPTGS2GLO1
SCHEMBL19236353 0.85 IAPP (0.70) AKR1B1AKR1B10MAOBPTGS2GLO1
SCHEMBL22328172 0.84 RAB9A (0.66) AKR1B1AKR1B10MAOBPTGS2GLO1
Bisdemethoxycurcumin SCHEMBL28163045 0.83 AKR1B1 (0.96) AKR1B1AKR1B10MAOBPTGS2GLO1
SCHEMBL27699740 0.82 CYP1A2 (0.62) AKR1B1AKR1B10MAOBPTGS2GLO1
SCHEMBL22214054 0.82 IAPP (0.59) AKR1B1AKR1B10MAOBPTGS2GLO1
SCHEMBL3401728 0.82 HSD11B1 (0.62) AKR1B1AKR1B10MAOBPTGS2GLO1
SCHEMBL3401725 0.82 HSD11B1 (0.62) AKR1B1AKR1B10MAOBPTGS2GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847318-B1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES MARRONE BIO INNOVATIONS INC (US) 2019-01-23 EP claimed
US-20250011293-A1 LEUKOTRIENE SYNTHESIS INHIBITORS NAEGIS PHARMACEUTICALS INC. (CA) 2025-01-09 US disclosed
US-11976052-B2 Leukotriene synthesis inhibitors NAEGIS PHARMACEUTICALS INC. (CA) 2024-05-07 US disclosed
US-20220064132-A1 LEUKOTRIENE SYNTHESIS INHIBITORS NAEGIS PHARMACEUTICALS INC. (CA) 2022-03-03 US disclosed
US-20210227833-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES MARRONE BIO INNOVATIONS, INC. (US) 2021-07-29 US disclosed
US-11013236-B2 Pesticidal Flavobacterium strain and bioactive compositions metabolites and uses MARRONE BIO INNOVATIONS, INC. (US) 2021-05-25 US disclosed
US-11013236-B2 Pesticidal Flavobacterium strain and bioactive compositions metabolites and uses MARRONE BIO INNOVATIONS, INC. (US) 2021-05-25 US disclosed
EP-2847318-B1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES MARRONE BIO INNOVATIONS INC (US) 2019-01-23 EP disclosed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 US disclosed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 US disclosed
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES PRO FARM GROUP, INC. 2015-01-29 US disclosed
WO-2013138398-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS, METABOLITES AND USES MARRONE BIO INNOVATIONS, INC. (US) 2013-09-19 WO disclosed
US-5135955-A Anticoagulants or antifungal activity ELI LILLY AND COMPANY (US) 1992-08-04 US disclosed
EP-0339878-A2 Propanamine derivatives ELI LILLY AND COMPANY (US) 1989-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220064132-A1 LEUKOTRIENE SYNTHESIS INHIBITORS LTC4S, LTB4R2, LTA4H AKR1B1 619/4885AKR1B10 654/4885MAOB 758/4885
US-20210227833-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES BLVRB, PRDX6, ACHE AKR1B1 2910/4885AKR1B10 3354/4885MAOB 224/4885
US-20150031534-A1 PESTICIDAL FLAVOBACTERIUM STRAIN AND BIOACTIVE COMPOSITIONS METABOLITES AND USES BLVRB, PRDX6, ACHE AKR1B1 2910/4885AKR1B10 3354/4885MAOB 224/4885
US-11013236-B2 Pesticidal Flavobacterium strain and bioactive compositions metabolites and uses BLVRB, PRDX6, ACHE AKR1B1 2910/4885AKR1B10 3354/4885MAOB 224/4885
US-11976052-B2 Leukotriene synthesis inhibitors LTC4S, LTB4R2, LTA4H AKR1B1 619/4885AKR1B10 654/4885MAOB 758/4885
US-20250011293-A1 LEUKOTRIENE SYNTHESIS INHIBITORS LTC4S, LTB4R2, LTA4H AKR1B1 619/4885AKR1B10 654/4885MAOB 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.