Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736905 | 0.90 | ALOX5 (0.39) | F10ALOX5KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7277331 | 0.84 | F10 (0.40) | F10KDM4EBRD4ALDH1A1BRPF1 | |
| SCHEMBL9736934 | 0.84 | NPSR1 (0.33) | KDM4E | |
| SCHEMBL9194883 | 0.81 | PDE4A (0.36) | — | |
| SCHEMBL9735809 | 0.81 | MEN1 (0.35) | ALDH1A1 | |
| SCHEMBL7268034 | 0.76 | ALOX5 (0.40) | F10ALOX5ALDH1A1SMN1; SMN2 | |
| SCHEMBL8085330 | 0.76 | F10 (0.40) | F10ELOVL6KDM4EBRD4ALDH1A1 | |
| SCHEMBL7276973 | 0.75 | F10 (0.33) | F10 | |
| SCHEMBL8090551 | 0.75 | RARA (0.41) | ALOX5KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7277136 | 0.75 | S100A4 (0.38) | F10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |