Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736934 | 0.85 | NPSR1 (0.33) | MAPT | |
| SCHEMBL7268307 | 0.84 | ALDH1A1 (0.39) | MEN1KMT2ACHRM2HTR1AADRA2A | |
| SCHEMBL9194883 | 0.82 | PDE4A (0.36) | HTR1ACYP3A4 | |
| SCHEMBL9736905 | 0.81 | ALOX5 (0.39) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9735586 | 0.81 | F10 (0.39) | ALDH1A1 | |
| SCHEMBL8128550 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2ACHRM2HTR1AADRA2A | |
| SCHEMBL9737279 | 0.79 | CHRM2 (0.34) | MEN1KMT2ACHRM2HTR1AADRA2A | |
| SCHEMBL8090151 | 0.78 | ALDH1A1 (0.36) | MEN1KMT2ACHRM2HTR1AADRA2A | |
| SCHEMBL8090555 | 0.78 | TDP1 (0.37) | MEN1KMT2ACHRM2HTR1AADRA2A | |
| SCHEMBL9735458 | 0.77 | NR1H4 (0.39) | MEN1KMT2AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |