Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977041 | 0.91 | HPGD (0.31) | HPGDRAB9A | |
| SCHEMBL974813 | 0.82 | HPGD (0.33) | HTTRECQLHPGDALDH1A1RAB9A | |
| SCHEMBL975290 | 0.79 | VCAM1 (0.36) | HTTHPGDALDH1A1RAB9A | |
| SCHEMBL973560 | 0.79 | SCN9A (0.34) | HTTRECQL | |
| SCHEMBL3540542 | 0.72 | LMNA (0.31) | HPGD | |
| SCHEMBL977040 | 0.70 | SCN9A (0.34) | HTTRECQL | |
| SCHEMBL9051631 | 0.67 | GAA (0.40) | HTTHPGDALDH1A1RAB9A | |
| SCHEMBL9492204 | 0.67 | KEAP1 (0.38) | HPGDALDH1A1RAB9A | |
| SCHEMBL3540540 | 0.66 | POLB (0.34) | — | |
| SCHEMBL9419230 | 0.66 | POLB (0.33) | HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541611-B2 | Bifunctional phenyl iso(thio)cyanates, processes and intermediates products for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2013-09-24 | — | — | US | disclosed |
| US-20120271049-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2012-10-25 | — | — | US | disclosed |
| US-8232421-B2 | Bifunctional phenyl ISO (THIO) cyanates, processes and intermediates for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2012-07-31 | — | — | US | disclosed |
| US-20110009640-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2011-01-13 | — | — | US | disclosed |
| US-7820846-B2 | by phosgenation of an aminobenzoylsulfamic acid amide intermediate; prepared from a p-nitrobenzoyl chloride or benzoate and a sulfamic acid amide and reducing the nitrobenzoylsulfamic acid amide; isocyanates are crop protection agents | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-26 | — | — | US | disclosed |
| US-7737275-B2 | Method for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2010-06-15 | — | — | US | disclosed |
| US-20060293520-A1 | Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | US | disclosed |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293520-A1 | Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils | HPRT1, TH, METTL3 | HTT 625/4885RECQL 1642/4885HPGD 1550/4885 |
| US-20120271049-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION | TST, IDO1, TMT1A | HTT 110/4885RECQL 2201/4885HPGD 492/4885 |
| US-20110009640-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | TST, IDO1, IDO2 | HTT 134/4885RECQL 2294/4885HPGD 477/4885 |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | TST, TMT1A, IDO1 | HTT 129/4885RECQL 2302/4885HPGD 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.