Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065 | 0.78 | MDM2 (0.68) | MDM2LMNACES2CES1ALKBH5 | |
| SCHEMBL9735929 | 0.77 | OPRM1 (0.44) | MDM2LMNAL3MBTL1HSD17B10MAPK1 | |
| SCHEMBL9736835 | 0.74 | ALDH1A1 (0.47) | MDM2LMNACES2CES1ALKBH5 | |
| SCHEMBL31370201 | 0.71 | TYR (0.55) | LMNAADRA2AHTR2AKCNH2KMT2A | |
| SCHEMBL29926764 | 0.71 | MDM2 (0.53) | MDM2LMNACES2CES1ALKBH5 | |
| SCHEMBL10988389 | 0.71 | MDM2 (0.53) | MDM2CES2CES1KMT2AL3MBTL1 | |
| SCHEMBL10829586 | 0.71 | LDHA (0.58) | MDM2CES2CES1KMT2AALDH1A1 | |
| SCHEMBL10830533 | 0.71 | ALDH1A1 (0.56) | MDM2LMNAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2985359 | 0.70 | CES1 (0.54) | MDM2LMNACES2CES1ALKBH5 | |
| SCHEMBL289556 | 0.69 | PGR (0.53) | MDM2LMNACES2CES1ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118685-A | Antiarrhythmia agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |