SCHEMBL975434

SCHEMBL975434

Cn1c2c[c]ccc2c2cc[c]cc21

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.44
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194516 0.89 GPR3 (0.64) GPR3KDM4EMEN1ALDH1A1MAPT
SCHEMBL2183525 0.82 KDM4E (0.41) GPR3KDM4EMEN1ALDH1A1MAPT
SCHEMBL975060 0.80 GPR3 (0.44) GPR3KDM4EMEN1ALDH1A1MAPT
SCHEMBL193899 0.76 GPR3 (0.64) GPR3KDM4EMEN1ALDH1A1MAPT
SCHEMBL973713 0.76 HPGD (0.37) KDM4EALDH1A1MAPTHPGDHTT
SCHEMBL976299 0.75 ALDH1A1 (0.39) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL975310 0.73 PGR (0.44) KDM4EMEN1ALDH1A1HPGDKMT2A
SCHEMBL17673493 0.72 IMPDH2 (0.32)
SCHEMBL552070 0.71 PIK3CD (0.43) KDM4EMEN1ALDH1A1HTTKMT2A
SCHEMBL6420678 0.71 PSEN1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475937-B2 Silicone composition and organic light-emitting diode DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
EP-2262861-B1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING (US) 2012-09-19 EP disclosed
US-20110017986-A1 Silicone Composition and Organic Light-Emitting Diode DOW CORNING CORPORATION 2011-01-27 US disclosed
EP-2262861-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE Dow Corning Corporation (US) 2010-12-22 EP disclosed
WO-2009120434-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING CORPORATION (US) 2009-10-01 WO disclosed