Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740084 | 0.90 | CNR2 (0.36) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL9732736 | 0.84 | KDM4E (0.33) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL9737886 | 0.79 | TLK2 (0.32) | ALDH1A1KDM4ESMN1; SMN2S100A4TLK2 | |
| SCHEMBL9733368 | 0.75 | ALOX5 (0.36) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9737102 | 0.70 | CNR2 (0.37) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL9737735 | 0.67 | S100A4 (0.35) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9735503 | 0.67 | ALOX5 (0.35) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL9372031 | 0.67 | KDM4E (0.33) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL9735400 | 0.65 | KDM4E (0.35) | ALDH1A1KDM4ELMNANPC1RAB9A | |
| SCHEMBL9737676 | 0.65 | ALDH1A1 (0.39) | ALDH1A1RAB9AMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |