Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737634 | 0.89 | KDM4E (0.48) | KDM4EDRD2SMN1; SMN2ALDH1A1APOBEC3A | |
| SCHEMBL9738233 | 0.89 | KCNQ3 (0.43) | KDM4EALDH1A1PTGS2NTRK1PIM1 | |
| SCHEMBL9737491 | 0.88 | PTGS2 (0.41) | KDM4ESMN1; SMN2ALDH1A1RAB9APTGS2 | |
| SCHEMBL9737961 | 0.86 | ALDH1A1 (0.43) | ALDH1A1PTGS2APOBEC3A | |
| SCHEMBL9738434 | 0.85 | KCNQ3 (0.41) | SMN1; SMN2ALDH1A1PTGS2IRAK4APOBEC3A | |
| SCHEMBL9737606 | 0.83 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1GAARAB9A | |
| SCHEMBL9737862 | 0.82 | TSPO (0.52) | — | |
| SCHEMBL9737699 | 0.78 | PTGDR2 (0.46) | KDM4EALDH1A1PTGS2IRAK4APOBEC3A | |
| SCHEMBL9737283 | 0.77 | PTGDR2 (0.47) | KDM4EALDH1A1RAB9APTGS2APOBEC3A | |
| SCHEMBL9737572 | 0.76 | TSPO (0.45) | KDM4EALDH1A1PTGS2APOBEC3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |