Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210089 | 0.81 | ACHE (0.46) | MEN1KMT2AKDM4ELMNAACHE | |
| SCHEMBL9211431 | 0.81 | HRH3 (0.47) | MEN1KMT2AKDM4ELMNAHRH3 | |
| Hydrochloric Acid SCHEMBL9206800 | 0.80 | DRD2 (0.41) | MEN1KMT2AKDM4ELMNAKCNH2 | |
| Hydrochloric Acid SCHEMBL10647386 | 0.79 | KDM4E (0.44) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL9215938 | 0.79 | HRH3 (0.46) | MEN1KMT2AKDM4ELMNAHRH3 | |
| SCHEMBL9214779 | 0.76 | PRMT5 (0.43) | SIGMAR1 | |
| SCHEMBL9206955 | 0.76 | DRD2 (0.44) | MEN1KMT2AKDM4ELMNAKCNH2 | |
| Hydrochloric Acid SCHEMBL9204880 | 0.75 | CCR2 (0.38) | MEN1KMT2AKDM4ELMNAHRH3 | |
| SCHEMBL12401212 | 0.75 | SIGMAR1 (0.51) | MEN1KMT2ALMNATSHRACHE | |
| Hydrochloric Acid SCHEMBL9208073 | 0.74 | PRMT5 (0.40) | KDM4ELMNATSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |