Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739164 | 0.98 | HRH3 (0.51) | HRH3TDP1HTR2AHTR7HTR6 | |
| SCHEMBL9740331 | 0.98 | HRH3 (0.51) | HRH3TDP1HTR2AHTR7HTR6 | |
| SCHEMBL9739808 | 0.86 | HRH3 (0.41) | HRH3 | |
| Hydrochloric Acid SCHEMBL9739352 | 0.85 | ADRA1B (0.39) | HRH3HTR2AHTR7MEN1KMT2A | |
| SCHEMBL9739061 | 0.83 | ACHE (0.40) | DRD2DRD4 | |
| SCHEMBL9740802 | 0.83 | SIGMAR1 (0.45) | — | |
| SCHEMBL9739652 | 0.81 | ADRA1B (0.45) | HRH3HTR1ADRD2DRD4 | |
| SCHEMBL9207074 | 0.80 | GRM5 (0.42) | HRH3 | |
| SCHEMBL9206705 | 0.80 | CHRNB2 (0.45) | HRH3TDP1 | |
| Hydrochloric Acid SCHEMBL9213427 | 0.79 | GRM5 (0.42) | HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |