Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740308 | 0.90 | KDM4E (0.51) | SPHK1KDM4ESPHK2ALDH1A1PPARD | |
| SCHEMBL9739559 | 0.85 | POLB (0.46) | SPHK1ALDH1A1MAPTMEN1HRH3 | |
| SCHEMBL9740178 | 0.81 | HRH3 (0.48) | SPHK1ALDH1A1MAPTKMT2AHRH3 | |
| SCHEMBL9211609 | 0.80 | KDM4E (0.55) | HTR1AHTR7L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9741170 | 0.76 | FAAH (0.52) | SPHK1SPHK2 | |
| SCHEMBL11448054 | 0.72 | KDM4E (0.59) | L3MBTL1KDM4EHRH3 | |
| SCHEMBL9740303 | 0.71 | HRH3 (0.60) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7249465 | 0.71 | CHRNB4 (0.49) | L3MBTL1ALDH1A1HRH3NPC1RAB9A | |
| SCHEMBL7247932 | 0.71 | LTA4H (0.67) | HTR1AHRH3 | |
| SCHEMBL7039538 | 0.71 | HTR7 (0.59) | HTR1AHTR7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |