Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739220 | 0.93 | HRH3 (0.52) | HRH3KDM4EKMT2AALDH1A1CHRNB4 | |
| SCHEMBL9211609 | 0.91 | KDM4E (0.55) | HRH3KDM4EKMT2AALDH1A1CHRNB4 | |
| SCHEMBL9739552 | 0.91 | CHRNB2 (0.57) | HRH3KDM4EKMT2AALDH1A1CHRNB4 | |
| SCHEMBL9210505 | 0.88 | HRH3 (0.57) | HRH3KDM4EKMT2AALDH1A1HTR2A | |
| SCHEMBL9205099 | 0.86 | HRH3 (0.48) | HRH3KDM4EKMT2AALDH1A1HTR2A | |
| SCHEMBL9208504 | 0.85 | HRH2 (0.49) | HRH3KDM4EKMT2AALDH1A1CHRNB4 | |
| SCHEMBL9740308 | 0.81 | KDM4E (0.51) | HRH3KDM4EKMT2AALDH1A1CHRNB4 | |
| SCHEMBL9205156 | 0.78 | CHRNB2 (0.54) | HRH3KDM4EKMT2AALDH1A1CHRNB4 | |
| SCHEMBL9206438 | 0.78 | HRH3 (0.64) | HRH3KDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9212384 | 0.77 | ADRA1A (0.52) | KDM4EKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |