Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739559 | 0.91 | POLB (0.46) | ALDH1A1HRH3SPHK1MAOAMAOB | |
| SCHEMBL9740276 | 0.90 | HTR1A (0.52) | KDM4EALDH1A1KMT2AHRH3SPHK1 | |
| SCHEMBL9740178 | 0.88 | HRH3 (0.48) | ALDH1A1KMT2AHRH3SPHK1 | |
| SCHEMBL9740303 | 0.81 | HRH3 (0.60) | KDM4EALDH1A1KMT2AHRH3CHRNB4 | |
| SCHEMBL9741170 | 0.80 | FAAH (0.52) | CHRNB4CHRNA3FAAHSPHK1SPHK2 | |
| SCHEMBL9739334 | 0.76 | TRPV6 (0.59) | ALDH1A1HRH3 | |
| SCHEMBL9739220 | 0.74 | HRH3 (0.52) | KDM4EALDH1A1KMT2AHRH3CHRNB4 | |
| SCHEMBL9211609 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1KMT2AHRH3CHRNB4 | |
| SCHEMBL11656348 | 0.72 | CHRNB4 (0.73) | KDM4EALDH1A1KMT2AHRH3CHRNB4 | |
| SCHEMBL9739552 | 0.71 | CHRNB2 (0.57) | KDM4EALDH1A1KMT2AHRH3CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |