SCHEMBL9740600

SCHEMBL9740600

Nc1c(Cl)cc2[nH]c[c]c2c1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3833231 0.67 AHR (0.31)
SCHEMBL2593530 0.63 CYP3A4 (0.56) ALDH1A1CYP3A4
SCHEMBL9742121 0.63 ALDH1A1 (0.34) ALDH1A1CYP3A4
SCHEMBL5074455 0.62 GAA (0.53) ALDH1A1CYP3A4
SCHEMBL321694 0.61 GPR84 (0.41)
SCHEMBL6928459 0.61 CYP3A4 (0.36) CYP3A4
SCHEMBL6011023 0.59 ALDH1A1 (0.42) ALDH1A1
SCHEMBL152187 0.59 CSNK2A1 (0.44)
SCHEMBL207906 0.59 HTR1A (0.31)
SCHEMBL7289940 0.59 CYP3A4 (0.59) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175157-A Cardiovascular disorders BOEHRINGER INGELHEIM GMBH (DE) 1992-12-29 US disclosed