Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL10439416 | 1.00 | LMNA (0.80) | — | |
| Chloroform SCHEMBL558767 | 1.00 | — | — | |
| Chloroform SCHEMBL1014755 | 0.91 | — | — | |
| Chloroform SCHEMBL10949561 | 0.89 | LMNA (1.00) | — | |
| Chloroform SCHEMBL10950487 | 0.89 | LMNA (1.00) | — | |
| Chloroform SCHEMBL2084455 | 0.89 | — | — | |
| Chloroform SCHEMBL88 | 0.89 | — | — | |
| Chloroform SCHEMBL30536988 | 0.89 | — | — | |
| Chloroform SCHEMBL28447144 | 0.84 | — | — | |
| Chloroform SCHEMBL8631228 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114053399-A | Tilapia mossambica streptococcus oral vaccine and preparation method thereof | 广东渔跃生物技术有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-114010700-A | Preparation method and application of noninvasive dermal penetration technology transdermal absorbent containing traditional Chinese medicine effective components | 哈尔滨职业技术学院 | 2022-02-08 | — | — | CN | claimed |
| CN-110082470-B | Detection method of san Tan Ning syrup | 四川逢春制药有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-107811970-B | Xilipaeg multivesicular liposome and preparation method thereof | 江苏艾立康药业股份有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-110038069-A | A kind of agalloch eaglewood Compatible Granule and preparation method thereof | 南京上元堂沉香生物科技有限公司 | 2019-07-23 | — | — | CN | claimed |
| CN-106518634-B | A kind of preparation method of photocatalysis α-dione compounds | 大连理工大学 | 2019-03-05 | — | — | CN | claimed |
| CN-107811970-A | West pa lattice multivesicular liposome and preparation method thereof | 江苏艾立康药业股份有限公司 | 2018-03-20 | — | — | CN | claimed |
| CN-107760496-A | A kind of cold soap preparation method of agalloch eaglewood ancient prescription for improving sleeping eyes quality | 广东中澔柏画健康药业有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-106518634-A | Preparing method of photocatalytic alpha-diketone compound | 大连理工大学 | 2017-03-22 | — | — | CN | claimed |
| CN-103869041-B | A kind of detection method of cough-relieving combination of oral medication | 迪沙药业集团有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-101011566-A | Medicine composition for treating chronic pelvic inflammatory disease, preparing method and quality controlling method thereof | BEIJING ASIA EAST BIO PHARM CO (CN) | 2007-08-08 | — | — | CN | claimed |
| CN-1954871-A | Yanhouqing preparation for treating throat disease and its preparation method and quality control method | BEIJING QIYUAN YIDE MEDICAL IN (CN) | 2007-05-02 | — | — | CN | claimed |
| CN-1308679-C | Quality detection method for oral liquid for curing infantile cough due to lung-heat | JIANGSU KANION PHARMACEUTICAL (CN) | 2007-04-04 | — | — | CN | claimed |
| CN-1886385-A | Crystals of phenylalanine derivatives and production methods thereof | AJINOMOTO KK (JP) | 2006-12-27 | — | — | CN | claimed |
| CN-1861153-A | Medicinal composition used for treating pharyngitis, its prepn. method and its quality control method | PANG LAIXIANG (CN) | 2006-11-15 | — | — | CN | claimed |
| CN-1840201-A | Polyethylene glycol prodrug of gambogicacid, its preparation method, formulation and use | UNIV CHINA PHARMA (CN) | 2006-10-04 | — | — | CN | claimed |
| CN-1799584-A | Chinese medicinal composition, its preparation process and quality control method | HUANG WEIMIN (CN) | 2006-07-12 | — | — | CN | claimed |
| CN-1739676-A | Chinese medicine mixture for treating leucopenia caused by tumor treating radiation therapy and chemotherapy and its quality control method | XIANYANG BUCHANG MEDICINE SCI (CN) | 2006-03-01 | — | — | CN | claimed |
| CN-1558229-A | Quality detection method for oral liquid for curing infantile cough due to lung-heat | 江苏康缘药业股份有限公司 | 2004-12-29 | — | — | CN | claimed |
| US-H346-H | Process for making compounds possessing anticholinesterase activity | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1987-10-06 | — | — | US | claimed |