SCHEMBL9746359

SCHEMBL9746359

CC(C)[Si](CCCl)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLC6A2 P23975 2/20 0.30
MAOA P21397 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
CYP2A6 P11509 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8344991 0.76 TRPA1 (0.36) TAAR1LMNATP53SLC6A2MAOA
SCHEMBL9746890 0.71
SCHEMBL9745993 0.70 TRPA1 (0.31) ALDH1A1
SCHEMBL9748153 0.67 TP53 (0.31) TP53
SCHEMBL9746373 0.67 TAAR1 (0.30) TAAR1SLC6A2
SCHEMBL381401 0.64 LMNA (0.37) TAAR1ALDH1A1LMNASLC6A2MAOA
SCHEMBL380701 0.64 TAAR1 (0.39) TAAR1ALDH1A1LMNASLC6A2MAOA
SCHEMBL9745935 0.64 LTA4H (0.32) ALDH1A1SMN1; SMN2SIGMAR1
SCHEMBL8992272 0.62 TAAR1 (0.37) TAAR1LMNASLC6A2MAOASLC6A4
Fluoride SCHEMBL27639902 0.62 MAOA (0.38) TAAR1ALDH1A1LMNASLC6A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed