Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24247730 | 0.77 | GRIK1 (0.56) | MAPTKIF11MEN1KMT2ATP53 | |
| SCHEMBL9746812 | 0.72 | SIRT2 (0.49) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3793284 | 0.72 | CA12 (0.58) | MAPTALDH1A1HPGDKIF11CYP2A6 | |
| SCHEMBL9747137 | 0.71 | GRIN2D (0.42) | MAPTALDH1A1HPGDHRH4MEN1 | |
| SCHEMBL9747658 | 0.71 | IMPDH2 (0.47) | — | |
| SCHEMBL834744 | 0.70 | CYP2A6 (0.68) | MAPTALDH1A1HPGDCYP2A6MEN1 | |
| SCHEMBL9747632 | 0.70 | LMNA (0.45) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9747366 | 0.70 | BRD4 (0.40) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL15960260 | 0.70 | ALDH1A1 (0.70) | MAPTALDH1A1HPGDCYP2A6MEN1 | |
| SCHEMBL7165962 | 0.70 | KDM4E (0.61) | MAPTALDH1A1HPGDKIF11CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |