Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27860967 | 0.91 | KMT2A (0.44) | KMT2ATSHRTP53MEN1LMNA | |
| SCHEMBL382685 | 0.89 | TSHR (0.47) | KMT2ATSHRTP53MEN1LMNA | |
| SCHEMBL482458 | 0.88 | TSHR (0.46) | KMT2ATSHRTP53MEN1LMNA | |
| Hydrogen Sulfide SCHEMBL2882266 | 0.88 | TSHR (0.46) | KMT2ATSHRTP53MEN1LMNA | |
| SCHEMBL18785766 | 0.84 | TP53 (0.42) | KMT2ATSHRTP53MEN1LMNA | |
| SCHEMBL18786007 | 0.83 | MLYCD (0.36) | KMT2ATSHRTP53MEN1LMNA | |
| SCHEMBL15216348 | 0.82 | ALDH1A1 (0.40) | KMT2ATSHRMEN1CYP2C19MAPT | |
| SCHEMBL383712 | 0.81 | PDCD1 (0.53) | KMT2ATSHRTP53MAPTPDCD1 | |
| SCHEMBL18785967 | 0.81 | POLB (0.43) | TSHRLMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18785759 | 0.81 | LMNA (0.42) | KMT2ATSHRTP53LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871761-B2 | Resist lower layer material, resist lower layer substrate comprising the material and method for forming pattern | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20080032231-A1 | Resist lower layer material, resist lower layer substrate comprising the material and method for forming pattern | SHIN-ETSU CHEMICAL CO., LTD. | 2008-02-07 | — | — | US | disclosed |