Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.38 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749382 | 0.86 | KDM4E (0.40) | KDM4EPKMFOLH1CPA3 | |
| SCHEMBL9749540 | 0.81 | KDM4E (0.46) | KDM4EPKM | |
| SCHEMBL9749094 | 0.73 | FOLH1 (0.41) | FOLH1CPA3GRM3 | |
| SCHEMBL9814887 | 0.69 | FOLH1 (0.61) | FOLH1GRM3 | |
| SCHEMBL9645833 | 0.68 | EGFR (0.43) | FOLH1CPA3 | |
| SCHEMBL1074418 | 0.67 | ALDH1A1 (0.56) | KDM4EPKM | |
| SCHEMBL21985480 | 0.66 | — | — | |
| SCHEMBL7779172 | 0.65 | ALDH1A1 (0.53) | KDM4EPKM | |
| SCHEMBL9814843 | 0.63 | CPB2 (0.59) | FOLH1GRM3 | |
| SCHEMBL9305760 | 0.63 | KMT2A (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |