Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.49 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14061940 | 0.82 | CA2 (0.69) | CRHBPCRHR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL10422318 | 0.82 | SLC25A1 (0.66) | CRHBPCRHR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL10422313 | 0.81 | NHERF1 (0.55) | CRHBPCRHR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL9749499 | 0.78 | CRHBP (0.52) | CRHBPCRHR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5172845 | 0.78 | NHERF1 (0.58) | CRHBPCRHR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL10422438 | 0.76 | LMNA (0.58) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8309888 | 0.76 | CRHBP (1.00) | CRHBPCRHR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8536389 | 0.75 | NHERF1 (0.55) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL29859684 | 0.75 | NHERF1 (0.55) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL10453008 | 0.75 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205079-B1 | ACID DISULFIMIDE TRIPHENODIOXAZINE DYES | BAYER AG (DE) | 1992-01-22 | — | — | EP | disclosed |
| EP-0255020-B1 | WATER SOLUBLE TRIPHENODIOXAZINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-09-19 | — | — | EP | disclosed |
| US-4895954-A | Dyeing wool, cellulose | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-23 | — | — | US | disclosed |
| US-4816574-A | FIBER-REACTIVE DYES FOR WOOL, CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | disclosed |
| EP-0255020-A2 | Water soluble triphenodioxazine compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |
| EP-0205079-A2 | Acid disulfimide triphenodioxazine dyes | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |