Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826339 | 0.80 | LMNA (0.36) | KDM4EXDHSLC22A12MAPTRAB9A | |
| SCHEMBL23555402 | 0.79 | ADRA2A (0.45) | KDM4EICAM1SELEVCAM1PTGS2 | |
| SCHEMBL9825320 | 0.78 | SLC9A1 (0.38) | KDM4ECA12ALOX5ALDH1A1MAOB | |
| SCHEMBL23555373 | 0.78 | ADRA2A (0.44) | KDM4EICAM1SELEVCAM1PTGS2 | |
| SCHEMBL9874491 | 0.76 | CNR2 (0.41) | CA12ALOX5ALDH1A1MAPTMAOB | |
| SCHEMBL9749622 | 0.76 | ALOX5 (0.46) | XDHSLC22A12ALOX5 | |
| SCHEMBL18574624 | 0.74 | SIGMAR1 (0.36) | KDM4EPTGS2CA12CA2MAPT | |
| SCHEMBL23555372 | 0.71 | CA2 (0.49) | PTGS2CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL8338224 | 0.71 | CA2 (0.49) | PTGS2CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL9825832 | 0.69 | RAB9A (0.41) | KDM4EXDHSLC22A12PTGS2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |