Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987891 | 0.68 | — | — | |
| SCHEMBL9751295 | 0.67 | LMNA (0.33) | ALDH1A1LMNAF2AKR1C1MEN1 | |
| SCHEMBL2503374 | 0.66 | AKR1C1 (0.47) | AKR1C1SMN1; SMN2MEN1KMT2AHSD11B1 | |
| SCHEMBL1702595 | 0.63 | MAOA (0.31) | MAOB | |
| SCHEMBL5168259 | 0.63 | OPRM1 (0.38) | ALDH1A1LMNAAKR1C1MAPTSMN1; SMN2 | |
| SCHEMBL434296 | 0.62 | KMT2A (0.33) | ALDH1A1AKR1C1MAPTMEN1KMT2A | |
| SCHEMBL4666989 | 0.62 | CYP2C9 (0.33) | ALDH1A1LMNAAKR1C1MAPTMEN1 | |
| SCHEMBL3819684 | 0.62 | P2RX1 (0.33) | MAPTMEN1KMT2AMAOB | |
| SCHEMBL5168618 | 0.62 | OPRM1 (0.31) | MAPTMAOB | |
| SCHEMBL7598738 | 0.62 | ALDH1A1 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396709-A4 | HUMAN LEUKOCYTE ELASTASE INHIBITORS AND METHODS OF PRODUCING AND USING SAME | — | 1991-05-22 | — | — | EP | claimed |
| EP-0396709-A1 | HUMAN LEUKOCYTE ELASTASE INHIBITORS AND METHODS OF PRODUCING AND USING SAME | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 1990-11-14 | — | — | EP | claimed |