Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327734 | 0.94 | ALOX5 (0.32) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL7329315 | 0.86 | ALOX5 (0.37) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL7324394 | 0.84 | TPSAB1 (0.40) | SIRT2SIRT1SIRT3CA2CA5A | |
| SCHEMBL7329900 | 0.83 | MMP8 (0.31) | TLR2 | |
| SCHEMBL7322873 | 0.83 | CES1 (0.35) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL7332099 | 0.82 | LNPEP (0.37) | HPGDCA2CA5A | |
| SCHEMBL10377223 | 0.81 | ERAP2 (0.36) | TLR2 | |
| SCHEMBL7329240 | 0.80 | CTSL (0.38) | SIRT2SIRT1SIRT3CA5ATLR2 | |
| SCHEMBL7324594 | 0.80 | CTSL (0.38) | SIRT2SIRT1SIRT3CA5ATLR2 | |
| SCHEMBL7322952 | 0.80 | CTSS (0.32) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015121-A1 | METHOD FOR TREATING FUNGAL INFECTION | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-17 | — | — | WO | claimed |
| WO-1991015121-A1 | METHOD FOR TREATING FUNGAL INFECTION | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-17 | — | — | WO | disclosed |