Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322813 | 0.94 | CTSD (0.37) | CTSDCASP1CA2CA5A | |
| SCHEMBL7324031 | 0.93 | CASP1 (0.38) | CTSDCASP1HPGDSMN1; SMN2 | |
| SCHEMBL7329312 | 0.84 | CTSD (0.42) | CTSDCASP1HPGDSMN1; SMN2 | |
| SCHEMBL9754459 | 0.83 | CTSD (0.34) | ERAP2ERAP1CTSDCASP1CA2 | |
| SCHEMBL9754438 | 0.82 | ALOX5 (0.32) | CA2CA5AHPGD | |
| SCHEMBL9754633 | 0.82 | LNPEP (0.39) | LNPEPERAP2ERAP1CTSDIL1RN | |
| SCHEMBL7321477 | 0.81 | CASP1 (0.46) | CTSDCASP1HPGD | |
| Hydrochloric Acid SCHEMBL7331042 | 0.81 | CASP1 (0.43) | LNPEPERAP2ERAP1CTSDCASP1 | |
| SCHEMBL7323405 | 0.81 | SYK (0.46) | ERAP2ERAP1CTSDCASP1IL1RN | |
| SCHEMBL7319638 | 0.81 | CTSK (0.46) | CTSDCASP1CTSBCTSKCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |