Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761080 | 0.73 | MAT2A (0.34) | ALDH1A1MAPTMAT2AHTTRAB9A | |
| SCHEMBL9762396 | 0.72 | MAPT (0.33) | MAPT | |
| SCHEMBL9762560 | 0.67 | PIK3CB (0.49) | ALDH1A1MAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL9762579 | 0.66 | KMT2A (0.46) | MAPTLMNAMEN1NPC1CDK2 | |
| SCHEMBL9761376 | 0.65 | MAPT (0.35) | ALDH1A1MAPTLMNAMEN1NPC1 | |
| SCHEMBL9762532 | 0.63 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9762507 | 0.63 | MAPT (0.39) | ALDH1A1MAPTSMN1; SMN2PKM | |
| SCHEMBL9762410 | 0.61 | ALOX15 (0.42) | ALDH1A1MAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL9761367 | 0.60 | ALOX15 (0.38) | ALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL9761190 | 0.59 | TSHR (0.37) | ALDH1A1MAPTSMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |