Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29216797 | 0.75 | LMNA (0.38) | LMNAALDH1A1KDM4ECYP3A4TRPM8 | |
| SCHEMBL7723641 | 0.75 | L3MBTL1 (0.36) | LMNAKDM4EL3MBTL1TSHRSLC6A2 | |
| SCHEMBL2572166 | 0.75 | L3MBTL1 (0.40) | LMNAALDH1A1KDM4ETP53L3MBTL1 | |
| SCHEMBL2038945 | 0.73 | ACHE (0.43) | LMNAALDH1A1CYP3A4TRPM8TP53 | |
| SCHEMBL7731821 | 0.73 | L3MBTL1 (0.35) | LMNAL3MBTL1ADRA2AADRA2BHTR2A | |
| O-Xylene SCHEMBL28066372 | 0.71 | LMNA (0.57) | LMNACYP3A4L3MBTL1TSHRACHE | |
| SCHEMBL29069502 | 0.70 | ALDH1A1 (0.35) | LMNAALDH1A1KDM4ECYP3A4TRPM8 | |
| SCHEMBL2124908 | 0.70 | TSHR (0.39) | LMNAALDH1A1KDM4ECYP3A4TRPM8 | |
| SCHEMBL4352608 | 0.69 | ALDH1A1 (0.38) | LMNAALDH1A1TSHRACHECYP2C19 | |
| SCHEMBL10766412 | 0.69 | CYP3A4 (0.37) | LMNAALDH1A1KDM4ECYP3A4TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997918-A | Benzthiazolium azo dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0105031-B1 | CATIONIC AZO DYESTUFFS | CIBA-GEIGY AG (CH) | 1989-01-04 | — | — | EP | disclosed |
| EP-0105031-A2 | Cationic azo dyestuffs | CIBA-GEIGY AG (CH) | 1984-04-04 | — | — | EP | disclosed |