SCHEMBL4352608

SCHEMBL4352608

CCOC(C)N(c1ccc(C)cc1)C(C)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CA7 P43166 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.32
ACHE P22303 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
FFAR1 O14842 1/20 0.31
CHRNA7 P36544 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4352158 0.83 TSHR (0.34) ALDH1A1TSHRRAB9AMEN1KMT2A
SCHEMBL2572166 0.82 L3MBTL1 (0.40) ALDH1A1TSHRRAB9ALMNA
SCHEMBL7723637 0.72 LMNA (0.36) ALDH1A1TSHRMEN1KMT2AMAOA
SCHEMBL29216795 0.72 ALDH1A1 (0.42) ALDH1A1TSHRMAOAMAOBCA7
SCHEMBL5376140 0.71 ALDH1A1 (0.41) ALDH1A1TSHRRAB9AMAOAMAOB
SCHEMBL7731814 0.71 LMNA (0.35) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL819703 0.71 ALDH1A1 (0.50) ALDH1A1TSHRMAOAMAOBCA7
SCHEMBL279002 0.69 AGXT (0.40) ALDH1A1TSHRRAB9AMAOBCYP2C19
SCHEMBL9762463 0.69 LMNA (0.37) ALDH1A1TSHRMEN1KMT2ACYP2C19
SCHEMBL28590655 0.68 L3MBTL1 (0.33) ALDH1A1MEN1KMT2AMAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-10-31 US disclosed
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-08-27 US disclosed
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP disclosed
US-11612548-B2 Radiopaque dental composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-03-28 US disclosed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP disclosed
EP-3624753-B1 DENTAL ADHESIVE COMPOSITION, PREPARATION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2022-03-30 EP disclosed
EP-3706708-B1 RADIOPAQUE DENTAL COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2022-01-12 EP disclosed
US-11160733-B2 Dental adhesive composition, preparation and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-11-02 US disclosed
US-20210085570-A1 ONE-PART DENTAL ADHESIVE COMPOSITION FOR FIXING DENTAL COMPOSITE MATERIALS 3M INNOVATIVE PROPERTIES COMPANY 2021-03-25 US disclosed
EP-3787588-A2 ONE-PART DENTAL ADHESIVE COMPOSITION FOR FIXING DENTAL COMPOSITE MATERIALS 3M Innovative Properties Company (US) 2021-03-10 EP disclosed
US-20200360240-A1 RADIOPAQUE DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2020-11-19 US disclosed
EP-3706708-A1 RADIOPAQUE DENTAL COMPOSITION 3M Innovative Properties Company (US) 2020-09-16 EP disclosed
EP-3624753-A1 DENTAL ADHESIVE COMPOSITION, PREPARATION AND USE THEREOF 3M Innovative Properties Company (US) 2020-03-25 EP disclosed
US-20200069532-A1 DENTAL ADHESIVE COMPOSITION, PREPARATION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2020-03-05 US disclosed
WO-2018213060-A1 DENTAL ADHESIVE COMPOSITION, PREPARATION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-11-22 WO disclosed
US-7615582-B2 One-pack type adhesive composition for dental use KURARAY MEDICAL INC. (JP) 2009-11-10 US disclosed
US-20070100020-A1 One-pack type adhesive composition for dental use KURARAY MEDICAL INC. (JP) 2007-05-03 US disclosed
EP-1695685-A1 ONE-PACK TYPE ADHESIVE COMPOSITION FOR DENTAL USE Kuraray Medical Inc. (JP) 2006-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials CDH1, F12, ACTN1 ALDH1A1 78/4885TSHR 4762/4885POLB 279/4885
US-20070100020-A1 One-pack type adhesive composition for dental use CDH1, COL1A1, COL2A1 ALDH1A1 419/4885TSHR 4681/4885POLB 511/4885
US-20200360240-A1 RADIOPAQUE DENTAL COMPOSITION RAD51, ESD, RARA ALDH1A1 768/4885TSHR 2385/4885POLB 383/4885
US-11612548-B2 Radiopaque dental composition RAD51, ESD, RARA ALDH1A1 768/4885TSHR 2385/4885POLB 383/4885
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials CDH1, F12, ACTN1 ALDH1A1 78/4885TSHR 4762/4885POLB 279/4885
US-20210085570-A1 ONE-PART DENTAL ADHESIVE COMPOSITION FOR FIXING DENTAL COMPOSITE MATERIALS CDH1, F12, ACTN1 ALDH1A1 78/4885TSHR 4762/4885POLB 279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.