Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764480 | 0.85 | MMP2 (0.43) | KDM4EMITFGAAMAPK1P4HB | |
| SCHEMBL9763136 | 0.83 | DRD4 (0.47) | SMN1; SMN2KDM4EMITFGAAMAPK1 | |
| SCHEMBL9764455 | 0.78 | MAOA (0.40) | KDM4EMITFGAAMAPK1P4HB | |
| SCHEMBL9763494 | 0.76 | DRD2 (0.47) | SMN1; SMN2NPC1BCHEMAOAACHE | |
| SCHEMBL9318691 | 0.76 | SLC2A1 (0.48) | KDM4EKMT2AALDH1A1MEN1BCHE | |
| SCHEMBL9764499 | 0.74 | KDM4E (0.45) | KDM4EMITFGAAMAPK1P4HB | |
| SCHEMBL9764397 | 0.73 | ACACB (0.43) | SMN1; SMN2GAAMAPK1LMNAALDH1A1 | |
| SCHEMBL9763710 | 0.72 | SIGMAR1 (0.43) | SMN1; SMN2NPC1MAOA | |
| SCHEMBL10477796 | 0.71 | KDM4E (0.40) | KDM4EMITFGAAMAPK1P4HB | |
| SCHEMBL9764540 | 0.71 | SIGMAR1 (0.55) | KDM4EMAPK1KMT2AMEN1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |