Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764480 | 0.77 | MMP2 (0.43) | KDM4EMAPK1BCHEACHEALDH1A1 | |
| SCHEMBL9318691 | 0.76 | SLC2A1 (0.48) | KDM4EBCHEMEN1ALDH1A1KMT2A | |
| SCHEMBL9764451 | 0.74 | SMN1; SMN2 (0.45) | KDM4EMAPK1BCHEACHEMEN1 | |
| SCHEMBL9763136 | 0.74 | DRD4 (0.47) | KDM4EMAPK1BCHEP4HBNPSR1 | |
| SCHEMBL9763494 | 0.73 | DRD2 (0.47) | BCHEACHEMAOACHRM2ADRB2 | |
| SCHEMBL9764455 | 0.72 | MAOA (0.40) | KDM4EMAPK1BCHEACHEP4HB | |
| SCHEMBL9764397 | 0.71 | ACACB (0.43) | MAPK1ALDH1A1GAA | |
| SCHEMBL10465009 | 0.70 | EPHX2 (0.51) | KDM4EMEN1ALDH1A1KMT2AHDAC3 | |
| SCHEMBL10417690 | 0.70 | MAOA (0.48) | KDM4EMAPK1BCHEACHEMAOA | |
| SCHEMBL9763151 | 0.70 | BCHE (0.49) | KDM4EMAPK1BCHEACHEP4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |