Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712597 | 0.89 | KEAP1 (0.70) | ALDH1A1KEAP1TDP1L3MBTL1ALOX5 | |
| SCHEMBL8962348 | 0.88 | ALDH1A1 (0.77) | ALDH1A1KEAP1TDP1L3MBTL1ALOX5 | |
| SCHEMBL497371 | 0.87 | KEAP1 (0.73) | ALDH1A1KEAP1TDP1L3MBTL1ALOX5 | |
| SCHEMBL107423 | 0.85 | KEAP1 (0.70) | ALDH1A1KEAP1TDP1L3MBTL1ALOX5 | |
| SCHEMBL5355399 | 0.83 | KEAP1 (0.75) | ALDH1A1KEAP1TDP1L3MBTL1FFAR1 | |
| SCHEMBL16274 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KEAP1TDP1L3MBTL1FFAR1 | |
| Hydrochloric Acid SCHEMBL27872269 | 0.82 | KEAP1 (0.72) | ALDH1A1KEAP1TDP1L3MBTL1FFAR1 | |
| SCHEMBL4077641 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KEAP1TDP1L3MBTL1ALOX5 | |
| SCHEMBL24241943 | 0.81 | ALOX5 (0.59) | ALDH1A1KEAP1TDP1L3MBTL1ALOX5 | |
| SCHEMBL7450667 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KEAP1TDP1L3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006567-A | Polycarbonates with high impact strength | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | disclosed |