Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.41 |
| ▸ | TOP2A | P11388 | 4/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768425 | 0.85 | ADRB2 (0.46) | — | |
| SCHEMBL9768420 | 0.83 | PARP1 (0.50) | HTT | |
| SCHEMBL9768406 | 0.81 | SMN1; SMN2 (0.52) | ALKHTT | |
| SCHEMBL10338976 | 0.79 | ALDH1A1 (0.41) | CDK4HTT | |
| SCHEMBL10668875 | 0.79 | KCNA3 (0.44) | ALK | |
| SCHEMBL9781524 | 0.78 | KMT2A (0.42) | HTT | |
| SCHEMBL9768414 | 0.78 | ADRB2 (0.47) | — | |
| SCHEMBL9768415 | 0.77 | XDH (0.55) | ALK | |
| SCHEMBL10614432 | 0.77 | ALDH1A1 (0.45) | HIF1AHTT | |
| SCHEMBL10667568 | 0.76 | ALDH1A1 (0.51) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073553-A | Treatment or prevention of osteoporosis | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |