Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9768695 | 0.99 | KDM4E (0.47) | KDM4EALDH1A1NR1I3MEN1KMT2A | |
| SCHEMBL9768706 | 0.86 | MAPT (0.44) | KDM4EALDH1A1NR1I3KMT2ATP53 | |
| SCHEMBL9768762 | 0.84 | NPC1 (0.40) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL9768785 | 0.81 | NPC1 (0.53) | ALDH1A1TP53CA2CA9 | |
| SCHEMBL9768744 | 0.79 | NR1I3 (0.44) | KDM4EALDH1A1NR1I3POLBTP53 | |
| SCHEMBL9768832 | 0.78 | MTNR1A (0.40) | MEN1KMT2APOLBTP53MAPT | |
| SCHEMBL9768826 | 0.77 | MAPT (0.41) | KDM4EALDH1A1NR1I3MEN1KMT2A | |
| SCHEMBL9768740 | 0.76 | CYP2D6 (0.53) | KDM4EALDH1A1NR1I3KMT2AL3MBTL1 | |
| SCHEMBL9768831 | 0.76 | ALDH1A1 (0.56) | KDM4EALDH1A1NR1I3MEN1KMT2A | |
| SCHEMBL9768774 | 0.76 | ALDH1A1 (0.43) | KDM4EALDH1A1NR1I3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011833-A | Antidepressant | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE (IT) | 1991-04-30 | — | — | US | claimed |